Best time to send cold email, by hour and day, from 2.0M emails

By , co-founder of Sales.co. Published October 22, 2026, updated November 9, 2026.

Updated November 9, 2026 at 5:00 AM ET · Data through October 25, 2026 (the newest 14 days are left out so replies can arrive) · 2,007,540 cold emails from 61 sending workspaces · generated from Sales.co's sending data

Send cold email between 10am and 7pm Eastern, any weekday, and stop worrying about the exact hour. In 2.01 million cold emails Sales.co sent from Oct 6, 2025 to Oct 25, 2026, every hour from 10am to 7pm got between 0.72% and 0.78% human replies per email. Emails sent in the 9pm, 12am and 1am hours got 0.04% to 0.25% (the 10pm and 11pm hours are not shown because one sender made most of those emails).

What this page adds: reply rates by send hour and weekday from one company's own sending, 2,007,540 emails and 10,072 human replies, with every reply tied to the hour of the email it answered. The page is generated from the data file, so the dates above are the dates of the numbers.

Quick answers · By hour · By day · Follow-ups · Method · FAQ

Quick answers

What is the best time to send a cold email?
Between 10am and 7pm Eastern. In Sales.co's 2.0M emails, each of those hours got 0.72% to 0.78% human replies per email, so the hour inside the working day barely mattered. The single best hour was 5pm (0.78%, 59,720 emails).
What is the worst time to send a cold email?
Late at night Eastern time. Emails sent in the 9pm, 12am and 1am hours got 0.04% to 0.25% human replies per email, against at least 0.72% in working hours, so even the best of those hours got about 3 times fewer.
What is the best day to send cold emails?
Any weekday. Sent in working hours (9am to 6pm Eastern), Monday to Friday ranged from 0.67% (Thursday) to 0.72% (Wednesday) human replies per email.
Should you send cold emails on the weekend?
Weekend emails sent in working hours got more replies per email in this data (Saturday 0.95%, Sunday 1.20%). They were only 7.6% of working-hour sends, and this data does not record which campaigns sent them, so test a weekend send on your own list before moving volume there.
How many cold email replies come from follow-ups?
26.7% of human replies and 23.7% of interested replies answered a follow-up rather than the first email (9,696 human replies where the step was recorded).
What reply rate should a cold email get?
Across all 2.0M emails, 0.50% got a human reply and 0.15% got an interested one, about one interested reply per 671 emails sent.

Reply rate by send hour

Inside the working day the hour hardly matters: from 10am to 7pm Eastern every hour landed between 0.72% and 0.78% human replies per email, on 1,016,730 emails. The drop comes at night: the 9pm, 12am and 1am hours got 0.04% to 0.25% (the 10pm and 11pm hours are not shown because one sender made most of those emails). Night is not uniformly low: without the largest sender, 10pm got 0.58% and 11pm got 0.09%. Remove the largest sender and the working-day band is 0.69% to 0.76%, so one company's schedule does not make the pattern.

Human reply rate per cold email by send hour, Eastern time Bars for each hour from 12am to 11pm Eastern. The hours from 10am to 7pm sit between 0.72% and 0.78%; the 9pm, 12am and 1am hours sit between 0.04% and 0.25%. 2,007,540 emails, Oct 6, 2025 to Oct 25, 2026. Human replies per email sent, by send hour (Eastern) n = 2,007,540 emails · Oct 6, 2025 to Oct 25, 2026 0.0% 0.2% 0.4% 0.6% 0.8% 12am: 0.04% (114,256 emails) 12am 1am: 0.14% (109,034 emails) 2am: 0.20% (41,026 emails) 3am: 0.32% (41,903 emails) 3am 4am: 0.33% (42,155 emails) 5am: 0.50% (34,485 emails) 6am: 0.55% (34,105 emails) 6am 7am: 0.54% (34,225 emails) 8am: 0.44% (38,162 emails) 9am: 0.63% (109,329 emails) 9am 10am: 0.72% (131,076 emails) 11am: 0.73% (128,183 emails) 12pm: 0.72% (136,243 emails) 12pm 1pm: 0.72% (135,533 emails) 2pm: 0.73% (132,309 emails) 3pm: 0.74% (133,131 emails) 3pm 4pm: 0.72% (125,959 emails) 5pm: 0.78% (59,720 emails) 6pm: 0.78% (34,576 emails) 6pm 7pm: 0.73% (27,779 emails) 8pm: 0.61% (36,440 emails) 9pm: 0.25% (21,808 emails) 9pm n/s n/s Black: hours starting 10am through 6pm (10am to 7pm). Source: Sales.co sending data. n/s: not shown, one sender made over 45% of that hour's emails.
Sent (Eastern)EmailsHuman reply rateInterested rateHuman rate, largest sender removed
12am to 1am114,2560.04%0.01%0.04%
1am to 2am109,0340.14%0.06%0.14%
2am to 3am41,0260.20%0.08%0.18%
3am to 4am41,9030.32%0.17%0.28%
4am to 5am42,1550.33%0.13%0.29%
5am to 6am34,4850.50%0.22%0.51%
6am to 7am34,1050.55%0.25%0.57%
7am to 8am34,2250.54%0.20%0.59%
8am to 9am38,1620.44%0.17%0.47%
9am to 10am109,3290.63%0.18%0.65%
10am to 11am131,0760.72%0.19%0.75%
11am to 12pm128,1830.73%0.19%0.74%
12pm to 1pm136,2430.72%0.21%0.76%
1pm to 2pm135,5330.72%0.20%0.72%
2pm to 3pm132,3090.73%0.19%0.74%
3pm to 4pm133,1310.74%0.21%0.73%
4pm to 5pm125,9590.72%0.21%0.69%
5pm to 6pm59,7200.78%0.19%0.76%
6pm to 7pm34,5760.78%0.20%0.73%
7pm to 8pm27,7790.73%0.21%0.66%
8pm to 9pm36,4400.61%0.22%0.58%
9pm to 10pm21,8080.25%0.10%0.22%
10pm to 11pm132,209not shownnot shown0.58%
11pm to 12am173,894not shownnot shown0.09%

"Not shown": fewer than 2,000 emails in the hour, or one sending workspace made more than 45% of them. Source: Sales.co sending data, October 6, 2025 to October 25, 2026.

Why night sends may do worse: the hour is only part of it. Sending tools spread a day's volume across the hours each mailbox may send, so the night hours may carry a different mix of campaigns; the data does not show it. The database also does not record the recipient's time zone, so some night sends land in someone else's morning. The night rows show what late sends got; they do not prove the hour alone caused it.

Reply rate by day of the week

Weekdays are close to even. Sent in working hours (9am to 6pm Eastern), Monday to Friday ran from 0.67% on Thursday to 0.72% on Wednesday. Weekends got more replies per email, Saturday 0.95% and Sunday 1.20%, on far less volume: 7.6% of working-hour emails went out on a weekend.

DayEmails, 9am to 6pmHuman rateInterested rateEmails, all hoursHuman rate, all hours
Monday205,1210.71%0.19%343,2630.54%
Tuesday201,5740.69%0.17%346,4380.53%
Wednesday196,4930.72%0.19%339,3630.53%
Thursday208,2960.67%0.19%349,4780.50%
Friday197,3080.67%0.18%334,3880.49%
Saturday46,8680.95%0.34%137,8160.40%
Sunday35,8231.20%0.28%156,7940.44%

The all-hours columns include the night sends, which pull every day down. Source: Sales.co sending data, October 6, 2025 to October 25, 2026.

The strongest objection: weekend volume is small, and this data does not record campaigns, so it cannot say whether the senders who mail on a weekend simply had better lists. A higher weekend rate here is worth a split test on your own list before you move volume to it.

Timing across a sequence: first email vs follow-ups

26.7% of human replies and 23.7% of interested replies answered a follow-up; the rest answered the first email. That counts 9,696 human replies where the sending tool recorded which step they answered. For the reply rate of each email in a sequence, see cold email follow-up reply rates by step; for what to say in those follow-ups, see the follow-up email templates.

What to do with this

Schedule sends for 10am to 7pm Eastern, Monday to Friday. This data cannot tell you whether the recipient's own time zone matters, so test that on your list, and put the effort you would spend on picking the hour into the list and the first line. Across all 2.0M emails the human reply rate was 0.50% and the interested rate 0.15%, one interested reply per 671 emails. To see what that means for meetings at your volume, use the lead generation calculator.

If you would rather have someone run the sending, Sales.co runs done-for-you cold email from $2,000 a month for up to 10,000 emails, month-to-month. See pricing.

Method

Cite this: Sales.co, "Best time to send cold email, by hour and day", https://sales.co/research/best-time-to-send-cold-email, data through October 25, 2026.

Where to go next

11 cold email rules from 1.1M emails · follow-up reply rates by step · Cold email statistics · cold email response rates · cold email conversion rate benchmarks · follow-up email templates · cold email subject line grader · all Sales.co research

Sources

SALES.CO PRICING

FAQ

What is the best time to send a cold email?

Between 10am and 7pm Eastern. In Sales.co's 2.0M emails, each of those hours got 0.72% to 0.78% human replies per email, so the hour inside the working day barely mattered. The single best hour was 5pm (0.78%, 59,720 emails).

What is the worst time to send a cold email?

Late at night Eastern time. Emails sent in the 9pm, 12am and 1am hours got 0.04% to 0.25% human replies per email, against at least 0.72% in working hours, so even the best of those hours got about 3 times fewer.

What is the best day to send cold emails?

Any weekday. Sent in working hours (9am to 6pm Eastern), Monday to Friday ranged from 0.67% (Thursday) to 0.72% (Wednesday) human replies per email.

Should you send cold emails on the weekend?

Weekend emails sent in working hours got more replies per email in this data (Saturday 0.95%, Sunday 1.20%). They were only 7.6% of working-hour sends, and this data does not record which campaigns sent them, so test a weekend send on your own list before moving volume there.

How many cold email replies come from follow-ups?

26.7% of human replies and 23.7% of interested replies answered a follow-up rather than the first email (9,696 human replies where the step was recorded).

What reply rate should a cold email get?

Across all 2.0M emails, 0.50% got a human reply and 0.15% got an interested one, about one interested reply per 671 emails sent.